|“It not only shrinks your waistline, but miniaturizes you as well.”|
|— Cyrus Borg to the ninja in "The Titanium Ninja"|
The shrinking pill was a nano pill created by Cyrus Borg that shrinks one's waistline and miniaturizes them as well. It intended to shrink the Overlord, but instead shrunk Pythor when he got in the Overlord's way.
At the Temple of Fortitude, Cyrus Borg gives them the ultimate weapon—a pill. Jay is angry that all they had was a pill. Borg then explains that it was no ordinary pill; it could make anyone shrink. Garmadon realizes that when he and Wu were still young, they use to play a game called Templegate Tigers that involves Wu hitting an object with their staff, and they would never lose. Using this thought Garmadon forms an idea: Wu and him would hit the pill straight into the Overlord's mouth. The shield is starting to break; Nya comes and destroys a couple of Nindroids, and buys some time for the ninja. Borg gives the ninja armor which protects them from some attacks from the Overlord.
The ninja go into Ninjago City, where they manage to make it to the Golden Master, who has created a massive spider web around Borg Tower using the Golden Power. Wu hits the pill, which heads straight to the Overlord's mouth, but Pythor sacrifices himself and swallows the pill instead. As a result, Pythor shrinks down to the size of a worm before being immediately chased away by the Falcon.
- It was originally created to be a diet pill, but it didn't work as that.