- Not to be confused with another resistance.
The Resistance was a team that Lloyd and Nya formed after the assumed deaths of the rest of the original ninja (Kai, Jay, Cole, and Zane) and Wu. The team was formed to oppose the newly-resurrected Lord Garmadon, Harumi, and the Sons of Garmadon, in a bid to end their tyrannical rule over Ninjago City.
Lloyd and Nya were almost kidnapped by Garmadon's forces, but then the other Elemental Masters who partook in the Tournament of Elements saved them, making good on their promise of helping the ninja if the need arose.
In retaliation for breaking into Borg Industries, the Sons of Garmadon raid the base and arrest everyone except Lloyd, Nya, Skylor, Dareth, and Mystake, sending them to Kryptarium Prison. Mystake was killed by Garmadon while attempting to have Skylor absorb his power.
As a result of Garmadon losing his power and reign of Ninjago, the Resistance dissolved with their goal successful.
After Destiny's Bounty was destroyed by the Colossus, Wu, the original ninja—Cole, Kai, Jay, and Zane—were all presumed deceased. Unbeknownst to their allies, however, they survived and were all transported to the first realm in existence.
Though struck with despair at his loss, Lloyd regrouped with Nya, Misako, and P.I.X.A.L. with the intention of fighting another day. In the meantime, Lord Garmadon's tyrannical rule over Ninjago City strengthened, as Harumi and the Sons of Garmadon maintained their hold on the city. In response to this and the loss of the ninja, Lloyd went into hiding to train.
While hiding, they are hunted by Mr. E and Killow as well as their grunts. The group discovers the ninja was not killed but teleported to somewhere before Garmadon's forces close in. They are then saved by the Elemental Masters.
With the help of the Resistance, Lloyd advertised an announcement of hope to all the people with the help of his allies. However, this led to the group's location to be discovered by Harumi.
Garmadon led an ambush of his followers on the garbage depot. This resulted in most of the members being captured and sent to Kryptarium Prison, though Lloyd and a few others manage to invade this.
- Lloyd Garmadon, the team's leader; also the Green Ninja, the Elemental Master of Energy, and the son of Lord Garmadon. He regains his power by refusing to fight his father, resulting in his father losing his powers.
- Nya, the team's second-in-command; also the Elemental Master of Water and the sister of Kai. She is also the girlfriend of Jay and close friend to Cole and Zane.
- P.I.X.A.L., also known as Samurai X; an android created by Cyrus Borg, who helps the ninja on their missions. She's also the love interest of Zane and the team's third-in-command and Lloyd's backup protector and friend.
- Misako, the wife of the newly-resurrected Lord Garmadon, and the mother of Lloyd, and history informant.
- Dareth, a great ally of the ninja who recently provided a safe haven for Misako and Wu, and self-proclaimed "Brown Ninja."
- Skylor, the Elemental Master of Amber and the daughter of the late Master Chen. She eventually turned on her father and helped the ninja. She is Kai's love interest and a great ally to the ninja.
- Mr. Pale, the Elemental Master of Light, who competed in the Tournament of Elements.
- Karlof, the Elemental Master of Metal, who competed in the Tournament of Elements.
- Griffin Turner, the Elemental Master of Speed, who competed in the Tournament of Elements.
- Shade, the Elemental Master of Shadow, who competed in the Tournament of Elements.
- Tox, the Elemental Master of Poison, who competed in the Tournament of Elements.
- Neuro, the Elemental Master of Mind, who competed in the Tournament of Elements.
- Mystake, an Oni, an ally of the ninja who owns a tea shop and knew the location of the other ninja and Wu, who were thought to have perished. She was killed off-screen by Garmadon.
- Ronin, an on/off ally of the ninja who was captured by the Sons of Garmadon. While he does not join The Resistance before the ninja return, he joins after the mass breakout and helps take down the Colossus.
- This is the second team formed by ninja to replace team members, the first being the Ninja Replacements in the erased timeline of Skybound, formed by Jay. Skylor, Ronin, and Dareth were members of both teams.
- Most of the Elemental Masters also return and join the team for the first time since their last appearance in the Tournament of Elements (aside from Skylor, Griffin Turner, Tox, and Karlof who have appeared after Season 4).
- All the captured members escape Kryptarium in "Green Destiny."